Category Archives: Pharmacology

Anesthesia, Pain, Pharmacology, Physiology

Episode 210: An overview of Pain with Steve Cohen

August 30, 2021 ACCRAC Leave a comment

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 210: An overview of Pain with Steve Cohen

00:00 /

In this 210th episode I welcome international pain expert Dr. Steve Cohen to the show to discuss pain in general, how we categorize it, how we try to treat it, and what the future holds.

CME: https://earnc.me/2FktxV

References:

Cohen et al. Chronic Pain 1. Lancet 2021; 397: 2082–97.

Knezevic et al. Low Back Pain. Published online. June 8, 2021. TheLancet.com

Random Recs:

Queen’s Gambit: Link

Shtisel: Link

The NYTimes Morning Newsletter: https://www.nytimes.com/series/us-morning-briefing

Critical Care, Neuro, Pharmacology

Episode 199: Pharmacology for the Neuro ICU with Salia Farrokh

April 26, 2021 ACCRAC Leave a comment

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 199: Pharmacology for the Neuro ICU with Salia Farrokh

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In this 199th episode I welcome Salia Farrokh to the show to discuss pharmacology in the neuro ICU. We discuss treatment for status epilepticus, ICP crisis, reversal of anticoagulants in ICH, neurostimulants in TBI and BP management in stroke.

CME: https://earnc.me/ngSiLR

Salia is on LinkedIn at https://www.linkedin.com/in/salia-farrokh-pharm-d-bcps-bcccp-845b1b38/

Random Recs:

The Riyria Revelations: https://en.wikipedia.org/wiki/Riyria_Revelations

The Happier Podcast: https://gretchenrubin.com/podcasts/

References Download

Anesthesia, Anesthetic agents, Key Words, Pharmacology, Show Notes

Episode 193: Keywords Part 15: Pharmacology of Inhaled Anesthetics

February 1, 2021 ACCRAC 2 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 193: Keywords Part 15: Pharmacology of Inhaled Anesthetics

00:00 / 38:53

In this 193rd episode I welcome Dr. Gillian Isaac back to the show to discuss another ABA Key Word topic. This time we discuss the pharmacology of inhaled anesthetic agents.

CME: https://earnc.me/hxOv4S

Outline by Dr. Brian Park

References: Barash Clinical Anesthesia 8th edition and Anesthesiahub.com

Random Recs:

Chess.com

A Woman of No Importance

Anesthesia, Pharmacology

Episode 186: What anesthesiologists need to know about cannabis with Jen Meeker

October 27, 2020 ACCRAC 2 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 186: What anesthesiologists need to know about cannabis with Jen Meeker

00:00 / 50:08

In this 186th episode I welcome Dr. Jennifer Meeker to the show to discuss the increased use of cannabis in the general population and what that means for anesthesiologists taking care of patients who may have acute or chronic use.

CME: https://earnc.me/Ui9inp

References:Download

Random Recs:

Tuesday Nights Cookbook: Link

Vertellis: https://vertellis.com

Anesthesia, Interactive, Key Words, Pharmacology

Episode 180: Keywords part 12 with Gillian Isaac: Local Anesthetics

August 4, 2020 ACCRAC 2 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 180: Keywords part 12 with Gillian Isaac: Local Anesthetics

00:00 / 44:32

In this 180th episode I welcome back Dr. Gillian Isaac for another ABA keyword episode. We review local anesthetics.

CME: https://earnc.me/LzzOvu

Also check out Episode 41 for an in-depth episode on local anesthetics

CORRECTION: At 28:58 I state that hyperventilation increases the seizure threshold. This is incorrect, it DECREASES the seizure threshold.

Reference: Barash Clinical Anesthesia 8th edition: Chapter on Local Anesthetics
Outline by Brian Park, MD

Local anesthetics block nerve conduction by?
a. Closing calcium channels
b. Decreasing intracellular sodium concentration
c. Decreasing K conductance
d. Causing extrusion of intracellular K
e. Inhibiting cellular influx of sodium

Discussion (4:44)

See full interactive post

Anesthesia, Key Words, Pharmacology, Regional, Show Notes

Episode 150: Keywords Part 6: Supraclavicular, Axillary and Benzos

November 26, 2019 ACCRAC Leave a comment

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 150: Keywords Part 6: Supraclavicular, Axillary and Benzos

00:00 / 38:09

In this 150th episode I welcome back Dr. Gillian Isaac to do another round of ABA keywords. We discuss 2 additional upper extremity blocks (supraclavicular and axillary) and then benzodiazepines.

CME: https://earnc.me/4aBzu8

Outline by April Liu Download

Anesthesia, Key Words, Pharmacology, Regional, Show Notes

Episode 139: Keywords Part 5: Succinylcholine and Interscalene Block

September 17, 2019 ACCRAC 3 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 139: Keywords Part 5: Succinylcholine and Interscalene Block

00:00 / 46:29

In this 139th episode I welcome Dr. Gillian Isaac back to the show to discuss another 2 ABA keywords, succinylcholine and interscalene brachial plexus block.

CME: https://earnc.me/WBEa4s

Outline by April Liu Download

Anesthesia, Key Words, Pharmacology, Show Notes

Episode 126: Key Words with Gillian Isaac Part 2: Ketamine and Laryngospasm

June 28, 2019 ACCRAC 2 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 126: Key Words with Gillian Isaac Part 2: Ketamine and Laryngospasm

00:00 / 32:48

In this 126th episode I welcome back Dr. Gillian Isaac to discuss 2 more ABA key words: Ketamine and Laryngospasm.

CME: https://earnc.me/GbYGLA

Outline By Brian Park:Download

Critical Care, Pharmacology, Resuscitation

Episode 119: STOP-IT Trial with Rob Sawyer

May 13, 2019 ACCRAC 2 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 119: STOP-IT Trial with Rob Sawyer

00:00 / 37:37

In this 119th episode I welcome Dr. Robert Sawyer to the show. Dr. Sawyer was the PI on the STOP-IT trial comparing a short course of antibiotics versus a longer course for complicated intraabdominal infections. We discuss the trial, the outcomes, and what the future of antimicrobial management in the surgical ICU may look like.

CME: https://earnc.me/jeCfMt

Reference:

STOP-IT Trial: https://www.nejm.org/doi/full/10.1056/NEJMoa1411162

Anesthesia, Anesthetic agents, ERAS, Pain, Pharmacology

Episode 109: Non-Opioid Adjuncts with Drs. Grant and Bicket part 2

February 21, 2019 ACCRAC 5 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 109: Non-Opioid Adjuncts with Drs. Grant and Bicket part 2

00:00 / 36:11

In this 109th episode we pick up where we left off in episode 108 and discuss the intraoperative use of non-opioid adjuncts.

CME: https://earnc.me/k6e6gK

References:

Wick EC, Grant MC and Wu CL. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques A Review. JAMA Surg. 2017;152(7):691-697.

Bahr MP, Williams BA. Esmolol, Antinociception, and Its Potential Opioid-Sparing Role in Routine Anesthesia Care. Regional Anesthesia and Pain Medicine. 2018:43(8):815-818.

Grant MC, Ouanes JP, Joshi BL. Perioperative Esmolol and Opioids: Is More Really Less? Regional Anesthesia and Pain Medicine. 2018:43(8):813-814.

IV Lidocaine: https://academic.oup.com/bjaed/article/16/9/292/1743710

Ketamine: https://www.ncbi.nlm.nih.gov/pubmed/29870457

Dextramethorphan: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755866