Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 223: The Glycocalyx with Marius Fassbinder
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In this 223rd episode I welcome Dr. Marius Fassbinder back to the show to discuss the glycocalyx. We discuss what it is, what roll it plays in fluid dynamics, and what we need to know about how it influences our fluid management.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 216: Intralipid for AFE
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In this 216th episode I discuss case reports of using Lipid Emulsion Therapy for Amniotic Fluid Embolus. Big thanks to Dr. Adam Olson for bringing this to my attention!
CME: Reflect on how this Podcast applies to your day-to-day and earn AMA PRA Category 1 CMEs here: https://earnc.me/sCY01P
References:
Eldor J and Kotlovker V. Intralipid for Amniotic Fluid Embolism (AFE)? Open Journal of Anesthesiology, 2012, 2, 127-133
Lynch W et al. Lipid Emulsion Rescue of Amniotic Fluid Embolism-Induced Cardiac Arrest: A Case Report. A&A Case Reports. 2017;8:64–66.
Gruzman I et al. INTRALIPID Rescue of Amniotic Fluid Embolism: from Theory to Existence. Journal of Health Science and Development. 2019: 2:1 (1-4).
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 161: Dual Training in Anesthesiology and Emergency Medicine
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In this 161st episode I welcome Drs. Regan and Lester to the show to discuss the country’s first combined Anesthesiology and Emergency Medicine dual training program.
CME: https://earnc.me/5Wuljl
Website for the program: https://www.hopkinsmedicine.org/emergencymedicine/combined-residency/
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 159: Postpartum hemorrhage with Juanita Henao
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In this 159th episode I welcome Dr. Juanita Henao to the show to discuss prevention and management of postpartum hemorrhage.
One CORRECTION: At about minute 4:30 Dr. Henao states that in women with PPH the mortality rate is 10% but what she meant to say is that PPH accounts for 10% of maternal deaths in the United States.
Thorneloe, J.C.A. Carvalho, K. Downey,M. Balki. Uterotonic drug usage in Canada: a snapshot of the practice in obstetric units of university-affiliated hospitals. Int J Obstet Anesth. 2019 Feb;37:45-51.
Hian Yan Voon , Haris Njoo Suharjono , Asrul Akmal Shafie , Mohamad Adam Bujang Carbetocin versus oxytocin for the prevention of postpartum hemorrhage: A meta-analysis of randomized controlled trials in cesarean deliveries. Taiwan J Obstet Gynecol. 2018 Jun;57(3):332-339.
WOMAN trial collaborators. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet. 2017 May 27;389(10084):2105-2116.
David H. Chestnut, Cynthia A Wong, Lawrence C Tsen, Warwick D Ngan Kee, Yaakov Beilin, Jill Mhyre. Chestnut’s Obstetric Anesthesia: Principles and Practice. Fifth edition. Chapter 38, Anterpartum and Postpartum, Hemorrhage.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 143: Fluid management and cardiac output monitors in ERAS with Michael Scott
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In this 143rd episode I welcome Dr. Michael Scott to the show to discuss fluid management in ERAS cases and how cardiac output monitoring may help us do that well.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 140: Transfusion Triggers and The TRICS 3 Trial with David Mazer
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In this 140th episode I welcome Dr. David Mazer to the show. Dr. Mazer was the PI and first author on the TRICS 3 trial looking at liberal versus restrictive transfusion strategies in moderate to high risk cardiac surgery patients published in the NEJM in 2017.
CME: https://earnc.me/6SR7cb
Dr. Mazer would like to add the following random recommendation: For a great combination of live jazz and good food and drinks in Toronto, check out the Jazz Bistro just up the street from St. Michael’s Hospital.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 135: A Case For Low Dose Norepinephrine
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In this 135th episode I discuss my argument for using low dose norepinephrine to treat or even prevent hypotension in the OR and ICU. I discuss the CENSER trial looking at early norepinephrine in sepsis as well as a paper looking at preemptive norepinephrine in open cystectomies and a review article of trials looking at pressor use in free flap surgery. Join in the conversation here with your comments and on the ACCRAC Facebook page and Twitter @accracpodcast and @jwolpaw.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 129: Vascular Access with Dave Berman
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In this 129th episode I welcome Dr. Dave Berman back to the show to discuss vascular access devices. We talk about what kinds of lines exist, how to choose, what the pros and cons are, and how to know what kind of flow you will get with a given catheter.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 119: STOP-IT Trial with Rob Sawyer
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In this 119th episode I welcome Dr. Robert Sawyer to the show. Dr. Sawyer was the PI on the STOP-IT trial comparing a short course of antibiotics versus a longer course for complicated intraabdominal infections. We discuss the trial, the outcomes, and what the future of antimicrobial management in the surgical ICU may look like.
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 106: Hydroxyethyl Starches with Marius Fassbinder
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In this 106th episode I welcome Dr. Marius Fassbinder to the show to discuss the use of hydroxyethyl starches.
CME: https://earnc.me/sFF08C
References:
1. Woodcock, T. E. & Woodcock, T. M. Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an
improved paradigm for prescribing intravenous fluid therapy. British Journal of Anaesthesia 108, 384–394 (2012).
2. Westphal, M. et al. Hydroxyethyl starches: different products–different effects. Anesthesiology 111, 187–202 (2009).
3. Brunkhorst, F. M. et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N. Engl. J. Med. 358, 125–139
(2008).
4. Perner, A. et al. Hydroxyethyl Starch 130/0.42 versus Ringer’s Acetate in Severe Sepsis. N. Engl. J. Med. 367, 124–134 (2012).
6. Myburgh, J. A. et al. Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care. N. Engl. J. Med. 367, 1901–1911
(2012).
7. Annane, D. et al. Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with
hypovolemic shock: the CRISTAL randomized trial. JAMA 310, 1809–1817 (2013).
8. Joosten, A. et al. Crystalloid versus Colloid for Intraoperative Goal-directed Fluid Therapy Using a Closed-loop System: A
Randomized, Double-blinded, Controlled Trial in Major Abdominal Surgery. Anesthesiology 128, 55–66 (2018).
9. Gillies, M. A. et al. Incidence of postoperative death and acute kidney injury associated with 6% hydroxyethyl starch use: systematic review and meta-analysis. British Journal of Anaesthesia 112, 25–34 (2014).
