Category Archives: Pharmacology

Critical Care, Interactive, Pharmacology, Show Notes

Episode 56: Bugs and Drugs Part 1 with Rachel Kruer

September 28, 2017 ACCRAC 3 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 56: Bugs and Drugs Part 1 with Rachel Kruer

00:00 / 55:44

In this episode, episode 56, I welcome Rachel Kruer to the show. Rachel is one of our amazing ICU pharmacists and we discuss common bacteria and the drugs we use to treat them. This is part 1 of a 2 part series that I’ll be doing with Rachel on this topic.

CME: https://earnc.me/1McYTq

Skip to specific topics:

Pharmacodynamics vs. Pharmacokinetics (1:08)
Categorizing Bacteria (7:10)
Beta-Lactams (12:10)
Aztreonam (19:40)
Carbapenems (21:20)
Case Examples (24:20)
Fluoroquinolones (30:36)
Vancomycin (33:15)
Aminoglycosides (35:31)
Macrolides (39:45)
Linezolid (40:33)
Daptomycin (43:05)
Sulfonamide Antibiotics (44:05)
Clindamycin (45:49)
Colistin (47:17)
Glycylcycline (48:43)
Metronidazole (Flagyl) (49:55)
Vancomycin Resistant Enterococcus (51:11)
Surgical Prophylaxis (53:40)

Outline by April Liu
See other interactive posts

Anesthesia, Anesthetic agents, OB, Pharmacology, Show Notes

Episode 53: Analgesia for C-section with Mike Hofkamp

August 11, 2017 ACCRAC 4 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 53: Analgesia for C-section with Mike Hofkamp

00:00 / 1:02:12

In this episode, episode 53, I welcome back Dr. Mike Hofkamp to discuss analgesia for cesarean delivery. We discuss indications for C-section, urgent and emergent sections, anesthetic techniques and associated complications, how to approach the difficult airway in a pregnant patient, and aspiration prophylaxis.

CME: https://earnc.me/r63bjW

Additional information:

Outline by Brian Park
Discussion references

Urgent cesarean section
Maternal indications (1:52)
Fetal indications (7:35)
Urgent (11:59) vs emergent (17:10)
See full interactive post

Anesthesia, Anesthetic agents, OB, Pharmacology

Episode 51: Labor Analgesia with Jacqueline Galvan

July 24, 2017 ACCRAC Leave a comment

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 51: Labor Analgesia with Jacqueline Galvan

00:00
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49:35

In this episode, episode 51, I welcome back Dr. Jacqueline Galvan to discuss labor analgesia. We cover opioids including remifentanil, nitrous oxide, neuraxial anesthesia and other nerve blocks.

CME: https://earnc.me/hlwk7u

References:

Hess PE, et al. An association between severe labor pain and cesarean delivery. Anesth Analg. 2000 Apr;90(4):881-6
Van den Bussche E. Why women prefer epidural analgesia during childbirth: the role of beliefs about epidural analgesia and pain catastrophizing. Eur J Pain. 2007 Apr;11(3):275-82.
Varposhti MR et al. Comparison of remifentanil: Entonox with Entonox alone in labor analgesia. Adv Biomed Res. 2013 Nov 30;2:87

Anesthesia, OB, Pharmacology, Show Notes

Episode 46: Obstetric Pharmacology and Fetal Assessment with Mike Hofkamp

June 8, 2017 ACCRAC 8 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 46: Obstetric Pharmacology and Fetal Assessment with Mike Hofkamp

00:00
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54:59

In this episode, episode 46, I welcome back Dr. Mike Hofkamp to discuss obstetric pharmacology and fetal assessment.

CME: https://earnc.me/xnT8gE

Outline by Brian Park: Outline

Anesthesia, Pharmacology, Show Notes

Episode 42: Post-op Nausea and Vomiting (PONV)

May 2, 2017 ACCRAC 2 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 42: Post-op Nausea and Vomiting (PONV)

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29:21

In this episode, episode 42, I discuss Post-op Nausea and Vomiting (PONV). I discuss risk factors, complications, treatment and prevention and side effects.

CME: https://earnc.me/31KodT

Outline by April Liu: Outline

UPDATE April, 2018: In this episode I mention that the evidence is not good for Midazolam in preventing PONV. However, a good friend and colleague, Dr. Michael Grant, did a nice meta-analysis of available trials which concluded that it actually does work fairly well. Check out his study:

Grant MC, Kim J, Page AJ, et al. The Effect of Intravenous Midazolam on Postoperative Nausea and Vomiting: A Meta-Analysis. Anesthesia & Analgesia: 2016:122(3); 656–663.

Anesthesia, Anesthetic agents, Critical Care, Pharmacology, Show Notes

Episode 41: Local Anesthetics

April 21, 2017 ACCRAC 10 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 41: Local Anesthetics

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24:15

In this episode, episode 41, I review local anesthetics including the mechanism of action, commonly used agents, pharmacodynamics and kinetics, toxicity and treatment, and common blocks.

CME: https://earnc.me/rbqGL8

Outline by April Liu: Outline

Anesthesia, Cardiac, Critical Care, Pharmacology

Episode 30: Management of anticoagulation for non-valvular a-fib

January 17, 2017 ACCRAC Leave a comment

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 30: Management of anticoagulation for non-valvular a-fib

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33:19

In this episode, episode 30, I discuss the new American College of Cardiology Guidelines for the periprocedural management of anticoagulation for patients with non-valvular atrial fibrillation. This includes whether to stop, when to stop, whether to bridge, how to bridge, and how and when to restart.

CME: https://earnc.me/522vst

Outline by Brian Park: AC for Afib Outline

Anesthesia, Anesthetic agents, Critical Care, Pharmacology, Show Notes

Episode 26: Sugammadex with Dr. Amit Prabhakar

December 21, 2016 ACCRAC 4 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 26: Sugammadex with Dr. Amit Prabhakar

00:00
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21:55

In this episode I welcome Dr. Amit Prabhakar, one of our critical care fellows, to the show to discuss Sugammadex, a relatively recently approved (in the USA) reversal agent for Rocuronium and Vecuronium.

CME: https://earnc.me/h9cIdh

Outline by Brian Park: Sugammadex outline

Anesthesia, Critical Care, Pharmacology, Show Notes

Episode 24: The Evils of Sodium Bicarbonate

December 11, 2016 ACCRAC 11 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 24: The Evils of Sodium Bicarbonate

00:00
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20:31

In this episode I first suggest you take a look at the recently published (ahead of print) VANCS study on the use of vasopressin as a sole agent in the treatment of vasoplegic shock. Then I review the reasons never to use sodium bicarbonate in lactic acidosis.

CME: https://earnc.me/3CX3ha

The Vancs study: https://www.ncbi.nlm.nih.gov/pubmed/27841822

The two articles I recommend on bicarb:

Forsythe: https://www.ncbi.nlm.nih.gov/pubmed/10631227

Sabatini: https://www.ncbi.nlm.nih.gov/pubmed/18322160

Outline by Brian Park: Outline

Anesthesia, Critical Care, Pharmacology, Show Notes

Episode 19: Vasoactive medications

November 11, 2016 ACCRAC 15 Comments

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 19: Vasoactive medications

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27:59

In this episode I review the receptors that vasoactive drugs act on. I then review the main vasoactive medications used in the OR and the ICU to treat acute hypotension and the ones used to treat acute hypertension.

CME: https://cmefy.com/moment?id=3VcC8Y8

Outline by April Liu: Outline