In this episode I review the common IV agents used in anesthesia excluding opioids. I cover Propofol, Barbiturates, Benzodiazepines, Ketamine, Etomidate and Dexmedetomidine.
NOTE: There is an error in the audio recording regarding the dosing units for dexmedetomidine. I say on the podcast that the dosing units are mcg/kg/min which is INCORRECT. The correct dosing units are mcg/kg/HOUR. I have corrected this in the accompanying slides. Thanks to Melanie Browder for picking this up!
Good luck to the recent graduates taking their written board exam on July 29th!
Slides to go along with the podcast are here: IV induction agents slides
5 thoughts on “Episode 10: IV Induction Agents”
Thank you for this podcast, as a practicing nurse anesthetist, I really enjoy getting refreshers (especially while jogging, as you suggest!). In this episode, you note the infusion dose of dexmedetomidine to be 0.2-1.5 mcg/kg/minute, and the correct unit for this is mcg/kg/hour, listeners do not get this mixed up! Generally in my practice when this is the only infusion I’m running, such as in bariatric surgery, I set the infusion at 0.6 mcg/kg/hour, leave it, and titrate my narcotics and volatile as needed.
Keep up the good work, I look forward to future episodes!
Melanie Browder, CRNA DNAP
Hi Melanie, thank you for pointing this out. You’re absolutely correct. The dosing units should be in mcg/kg/hour.
I love ACCRAC!! I’m an auditory learner and you do a wonderful job of articulating this information in an engaging manner! Thank you for the time and commitment that you put into this podcast! I appreciate you!
Kim Taylor, RN BSN CCRN
Commenting with regards to Ketamine section, had discussion with colleague re Ketamine mechanism of action as described during the podcast. Do you have any reference for the following as we couldn’t find; ”inhibition of NMDA glutamine input to GABA system centrally”
Thanks & keep up the good work!
I’m not sure I understand your question. Ketamine is an NMDA receptor antagonist. Through that antagonism it decreases GABA-ergic inhibitory neurotransmission. One reference: https://www.karger.com/Article/Fulltext/493425