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In this 192nd episode I welcome Dr. Gillian Isaac back to the show to discuss another ABA keyword, maternal physiology.
CME: https://earnc.me/Z3mGJv
References: Barash Clinical Anesthesia 8th edition and Anesthesiahub.com
How does carbon dioxide affect uterine blood flow? Would hypercarbia tend to increase or decrease blood flow?
From Dr. Isaac:
There are many studies out there but the bottom line is that carbon dioxide probably doesn’t have much effect on uterine blood flow. Estrogens and progesterone are the major factors affecting blood flow in vessels supplying the uterus. The factors that modulate, complement and support vasodilation and vasoconstriction are: PGE2, LH, oxytocin, cytokines, neurotransmitters and other local blood flow regulators.