This is the second of two episodes about opioid medications. In this episode I cover the pharmacokinetics and pharmacodynamics of opioids, some of the common uses for these medications, mixed agonist-antagonist compounds, opioid antagonists, and opioid interaction with other medications.
Slides to go along with this episode are here: Opioids part 2
This is the first of a 2 part series on opioid medications. In this first episode I will talk about how opioids are categorized and their effects on the different body systems. In the next episode I will discuss their pharmacokinetics and pharmacodynamics as well as their various uses and some details on mixed agonist/antagonists.
Slides to go along with this episode are here: Opioids part 1
PLEASE NOTE: Around minute 12 I say that auditory evoked potentials are the most sensitive to anesthetics. This is incorrect. I should have said visual evoked potentials. Thanks to Howard Zee for catching that!
In this episode I review the common IV agents used in anesthesia excluding opioids. I cover Propofol, Barbiturates, Benzodiazepines, Ketamine, Etomidate and Dexmedetomidine.
NOTE: There is an error in the audio recording regarding the dosing units for dexmedetomidine. I say on the podcast that the dosing units are mcg/kg/min which is INCORRECT. The correct dosing units are mcg/kg/HOUR. I have corrected this in the accompanying slides. Thanks to Melanie Browder for picking this up!
Good luck to the recent graduates taking their written board exam on July 29th!
Slides to go along with the podcast are here: IV induction agents slides
In this episode I review the basic medication setup for the operating room including premedication, induction, neuromuscular blockade, antibiotics, reversal and antiemetics. I discuss weight based dosing and comment on a few alternatives to consider once you have the basic setup down. This episode should be useful for new CA-1s getting started in the OR but I would also like to ask senior residents to comment on what their basic setup is and how it may differ from what I’ve mentioned here.
Here is a list of the medications I discuss: Basic med setup w dosing
There are a few announcements I wanted to make including:
Check out pedsanesthesia.net. Dr. Robert Greenberg, a pediatric anesthesiologist here at Johns Hopkins runs it and it has lots of great information and topics in pediatric anesthesiology.
If you have suggestions for a better website than this one please let me know!
If you know a good way to set up an email list serve for these kinds of announcements please let me know that as well.
And, finally, I address a surgeon’s comment to one of our residents that you should always use 100% fio2 when ventilating one lung during a thoracic case. Listen to the podcast for details but the bottom line is you should NOT use 100% oxygen unless you have to in order to prevent hypoxia.
Here is a link to a great review on this topics published last year in Critical Care: https://www.ncbi.nlm.nih.gov/pubmed/26278383
This is a very high yield episode to help you review for the anesthesia board exam. I cover the board key word section entitled gas laws which includes a focus on volatile anesthetics, their properties, and how they act on, and in, the human body.
Topics covered will include:
Vaporizer Types and safety features
Uptake and elimination
Effects of ventilation and circulation
Second gas effect
Nitrous Oxide in closed spaces
If you’d like to view the ppt slides that correspond to this podcast they can be downloaded here: Gas_Laws