In this 180th episode I welcome back Dr. Gillian Isaac for another ABA keyword episode. We review local anesthetics.
CME: https://earnc.me/LzzOvu
Also check out Episode 41 for an in-depth episode on local anesthetics
CORRECTION: At 28:58 I state that hyperventilation increases the seizure threshold. This is incorrect, it DECREASES the seizure threshold.
Reference: Barash Clinical Anesthesia 8th edition: Chapter on Local Anesthetics
Outline by Brian Park, MD
Local anesthetics block nerve conduction by?
a. Closing calcium channels
b. Decreasing intracellular sodium concentration
c. Decreasing K conductance
d. Causing extrusion of intracellular K
e. Inhibiting cellular influx of sodium
Discussion (4:44)